Norse Atlantic has suspended all flights to Los Angeles from May to October, including those from London.
A spokesperson said the decision to ground the services was due to the Middle East conflict.
They added: “Due to the continued increase in fuel constraint risks, fuel prices, and the resulting impact on our operating costs, we have had to make the difficult decision to suspend our LAX operations this summer, May to October.
“All affected customers will be proactively notified by Norse Atlantic Airways today where contact details are available.
“We sincerely apologise, but as a consequence of this fuel crisis, it is our responsibility to ensure we make this decision to maintain a sustainable airline for our passengers and colleagues.
The decision to suspend the LA route, from both Gatwick and from Rome, leaves Norse with just four schedule long-haul routes this summer, from Gatwick to New York JFK and Orlando, and from Athens and Rome to JFK.
It has also yet to confirm if it will resume its winter-only service later this year between Manchester and Bangkok.
